The burden of medication overuse headache and patterns of switching and discontinuation among triptan users: a systematic literature review.

ABSTRACT:

Background

A synthesis of real-world discontinuation and switching patterns among triptan users and rates of acute medication use among patients with medication overuse headache (MOH) is needed to better understand the burden among patients with migraine. The study objectives were to: (1) synthesize rates of switching and discontinuation from triptans; (2) characterize acute medication use among patients with MOH; and (3) describe the associated burden.

Methods

A systematic literature review was conducted, under the Preferred Reporting Items for Systematic Review guidelines, using MEDLINE/EMBASE from database inception to July 2019. The search strategy targeted studies of adults with migraine, and included terms related to migraine and its treatment. Continuous variables wer

SUBMITTER: Deighton AM 

PROVIDER: S-EPMC8561931 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature