The impact of cardiomotor rehabilitation on endothelial function in elderly patients with chronic heart failure.

ABSTRACT:

Background

To explore the effects of cardiac exercise rehabilitation on peripheral blood endothelial progenitor cells (EPC) in elderly patients with chronic heart failure.

Methods

80 elderly patients with chronic heart failure were selected from March 2017 to March 2019 and randomly divided into two groups (N = 40). The control group was treated routinely and walked freely for 30-60 min every day. The patients in the exercise rehabilitation group developed a cardiac exercise rehabilitation plan. Then, cardiac function and peripheral blood B-natriuretic peptide (BNP) levels in the two groups were compared. The cell viability, proliferation, apoptosis, and invasion ability of EPCs were detected. The levels of the PI3K/AKT pathway and eNOS and VEGF were compared.

Results

SUBMITTER: Chen J 

PROVIDER: S-EPMC8561974 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature