Different hypertension thresholds and cognitive decline: a pooled analysis of three ageing cohorts.

ABSTRACT:

Background

The 2017 American College of Cardiology (ACC)/American Heart Association (AHA) guidelines for high blood pressure (BP) in adults came up with a new definition of hypertension with a threshold BP level of 130/80 mmHg. But the 2018 European Society of Cardiology (ESC)/European Society of Hypertension (ESH) guidelines adhered to a conventional hypertension definition as BP ≥ 140/90 mmHg. We aimed to compare the trajectories of cognitive decline between participants with BP < 130/80 mmHg in all BP measurement waves and others with all BP < 140/90 mmHg.

Methods

This pooled analysis involved middle-aged and older participants from three nationally representative ageing cohorts, including the Health and Retirement Study (HRS), the English Longitudinal Study of Ageing (EL

SUBMITTER: Ma Y 

PROVIDER: S-EPMC8561998 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature