Modelling the impact of age-stratified public health measures on SARS-CoV-2 transmission in Canada.

ABSTRACT: Public health measures applied exclusively within vulnerable populations have been suggested as an alternative to community-wide interventions to mitigate SARS-CoV-2 transmission. With the population demography and healthcare capacity of Canada as an example, a stochastic age-stratified agent-based model was used to explore the progression of the COVID-19 epidemic under three intervention scenarios (infection-preventing vaccination, illness-preventing vaccination and shielding) in individuals above three age thresholds (greater than or equal to 45, 55 and 65 years) while lifting shutdowns and physical distancing in the community. Compared with a scenario with sustained community-wide measures, all age-stratified intervention scenarios resulted in a substantial epidemic resurgence, with hos

SUBMITTER: Gabriele-Rivet V 

PROVIDER: S-EPMC8562391 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature