Implementation and Impact of a β-Lactam Allergy Assessment Protocol in a Veteran Population.

ABSTRACT:

Background

Approximately 10% of the US population reports having a β-lactam allergy, although nearly 90% do not have a true immunoglobulin E (IgE)-mediated reaction. This misconception results in using nonpreferred antibiotics, leading to antimicrobial resistance and treatment failure. To evaluate, clarify, and clear β-lactam allergies, we implemented a pharmacist-driven β-lactam allergy assessment (BLAA) protocol and penicillin allergy clinic (PAC). The purpose of this study was to illustrate the BLAA process, including the pharmacist-run PAC, and assess the impact on allergy clearance.

Methods

Clinical pharmacy specialists (CPS) evaluated hospitalized veterans with β-lactam allergies, using the BLAA protocol. Eligible patients could later be seen in PAC. This was a retrosp

SUBMITTER: Mitchell AB 

PROVIDER: S-EPMC8562903 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature