Antiseizure medication adherence trajectories in Medicare beneficiaries with newly treated epilepsy.

ABSTRACT:

Objective

This study was undertaken to characterize trajectories of antiseizure medication (ASM) adherence in adults with newly treated epilepsy and to determine predictors of trajectories.

Methods

This was a retrospective cohort study using Medicare. We included beneficiaries with newly treated epilepsy (one or more ASM and none in the preceding 2 years, plus International Classification of Diseases codes) in 2010-2013. We calculated the proportion of days covered (proportion of total days with any ASM pill supply) for 8 quarters or until death. Group-based trajectory models characterized and determined predictors of trajectories.

Results

We included 24 923 beneficiaries. Models identified four groups: early adherent (60%), early nonadherent (18%), late adherent (11%

SUBMITTER: Terman SW 

PROVIDER: S-EPMC8563423 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature