Pharmacoinformatics-based investigation of bioactive compounds of Rasam (South Indian recipe) against human cancer.

ABSTRACT: Spice-rich recipes are referred to as "functional foods" because they include a variety of bioactive chemicals that have health-promoting properties, in addition to their nutritional value. Using pharmacoinformatics-based analysis, we explored the relevance of bioactive chemicals found in Rasam (a South Indian cuisine) against oxidative stress-induced human malignancies. The Rasam is composed of twelve main ingredients, each of which contains a variety of bioactive chemicals. Sixty-six bioactive compounds were found from these ingredients, and their structures were downloaded from Pubchem. To find the right target via graph theoretical analysis (mitogen-activated protein kinase 6 (MAPK6)) and decipher their signaling route, a network was built. Sixty-six bioactive compounds were used for i

SUBMITTER: Kalimuthu AK 

PROVIDER: S-EPMC8563928 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature