Focal Thyroid Incidentalomas on ¹⁸F-FDG PET/CT: A Systematic Review and Meta-Analysis on Prevalence, Risk of Malignancy and Inconclusive Fine Needle Aspiration.

ABSTRACT:

Background

The rising demand for ¹⁸F-fluorodeoxyglucose positron emission tomography with computed tomography (¹⁸F-FDG PET/CT) has led to an increase of thyroid incidentalomas. Current guidelines are restricted in giving options to tailor diagnostics and to suit the individual patient.

Objectives

We aimed at exploring the extent of potential overdiagnostics by performing a systematic review and meta-analysis of the literature on the prevalence, the risk of malignancy (ROM) and the risk of inconclusive FNAC (ROIF) of focal thyroid incidentalomas (FTI) on ¹⁸F-FDG PET/CT.

Data sources

A literature search in MEDLINE, Embase and Web of Science was performed to identify relevant studies.

Study selection

Studies providing information o

SUBMITTER: de Leijer JF 

PROVIDER: S-EPMC8564374 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature