Association between glycemic control and cardiovascular events in older Japanese adults with diabetes mellitus: An analysis of the Japanese medical administrative database.

ABSTRACT:

Aims/introduction

The relationship between glycated hemoglobin (HbA1c) and cardiovascular events in older adults was investigated using a Japanese administrative medical database.

Materials and methods

Anonymized medical data on patients with diabetes mellitus aged ≥65 years for the period from January 2010 to December 2019 were extracted from the EBM Provider database. The primary end-point was a composite of cardiovascular events, whereas the other end-points included severe hypoglycemia and fracture. The association between cardiovascular events and HbA1c at the index date (i.e., approximately 10 months after initial diabetes mellitus diagnosis) was evaluated using the Cox proportional hazards model.

Results

Among the 3,186,751 patients in the database, 3,946 older

SUBMITTER: Yokote K 

PROVIDER: S-EPMC8565425 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature