Ultrasonographic characteristics of major salivary glands in anti-centromere antibody-positive primary Sjogren's syndrome.

ABSTRACT:

Purpose

To investigate salivary gland ultrasonography (SGUS) findings in primary Sjögren's syndrome (pSS) patients positive for the anti-centromere antibody (ACA) and compare these with those in ACA-negative pSS patients.

Methods

We analyzed demographic, clinical, laboratory, and SGUS data of pSS patients who fulfilled the 2002 American-European Consensus Group classification criteria for pSS. SGUS findings of four major salivary glands (bilateral parotid and submandibular glands) were scored in five categories and compared between ACA-positive and ACA-negative pSS patients. Linear regression analysis was performed to elucidate the factors associated with SGUS score.

Results

In total, 121 pSS patients were enrolled (19, ACA-positive). The ACA-positive patients were ol

SUBMITTER: Min HK 

PROVIDER: S-EPMC8565722 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature