Evaluation of health benefits of sea lamprey (Petromyzon marinus) isolates using in vitro antiinflammatory and antioxidant assays.

ABSTRACT: Sea lamprey (Petromyzon marinus), a parasitic fish which survives on blood of other fishes, is consumed as a delicacy in many countries. Our earlier studies on sea lamprey compounds that showed potential to deter adult sea lampreys yielded several sterols, glycerides, free fatty acids, amino acids, organic acids and nitrogenous compounds. Therefore, this study was to assess the health-benefits of these compounds including additional isolates from HPLC fractions that kept aside due to lack of activity in sea lamprey deterrent assays. In vitro cyclooxygenase enzymes (COX-1 and -2) and lipid peroxidation (LPO) inhibitory assays, respectively, were used to determine antiinflammatory and antioxidant activities. Among the tested sterols, cholesteryl eicosapentaenoate and cholesteryl arachidonate

SUBMITTER: Dissanayake AA 

PROVIDER: S-EPMC8565778 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature