Variation in Use of Repurposed Medications Among Patients With Coronavirus Disease 2019. From The Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study: Coronavirus Disease 2019 Registry Investigator Group.

ABSTRACT:

Importance

At the start of the coronavirus disease 2019 pandemic, medications repurposed for management of coronavirus disease 2019 were used in the absence of clinical trial evidence.

Objectives

To describe the variation and evolution in use of repurposed medications for coronavirus disease 2019.

Design setting and participants

Observational cohort study of adults hospitalized with coronavirus disease 2019 between February 15, 2020, and April 12, 2021, across 76 United States and international hospitals within the Society of Critical Care Medicine's Discovery Viral Infection and Respiratory Illness Universal Study coronavirus disease 2019 registry.

Main outcomes and measures

Hospital variation was quantified using multivariable adjusted random effects logistic

SUBMITTER: Garcia MA 

PROVIDER: S-EPMC8565794 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature