Active screening for tuberculosis in high-incidence Inuit communities in Canada: a cost-effectiveness analysis.

ABSTRACT:

Background

Active screening for tuberculosis (TB) involves systematic detection of previously undiagnosed TB disease or latent TB infection (LTBI). It may be an important step toward elimination of TB among Inuit in Canada. We aimed to evaluate the cost-effectiveness of community-wide active screening for TB infection and disease in 2 Inuit communities in Nunavik.

Methods

We incorporated screening data from the 2 communities into a decision analysis model. We predicted TB-related health outcomes over a 20-year time frame, beginning in 2019. We assessed the cost-effectiveness of active screening in the presence of varying outbreak frequency and intensity. We also considered scenarios involving variation in timing, impact and uptake of screening programs.

Results

Given

SUBMITTER: Uppal A 

PROVIDER: S-EPMC8565977 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature