Frequency of Exposure to Impaired Fasting Glucose and Risk of Mortality and Cardiovascular Outcomes.

ABSTRACT:

Background

Metabolic abnormalities, such as impaired fasting glucose (IFG), are dynamic phenomena; however, it is unclear whether the timing of IFG exposure and cumulative exposure to IFG are related to cardiovascular disease (CVD) and mortality risk.

Methods

Data were extracted from a nationwide population-based cohort in South Korea for adults (n=2,206,679) who were free of diabetes and had 4 years of consecutive health examination data. Fasting blood glucose levels of 100 to 125 mg/dL were defined as IFG, and the number of IFG diagnoses for each adult in the 4-year period was tabulated as the IFG exposure score (range, 0 to 4). Adults with persistent IFG for the 4-year period received a score of 4.

Results

The median follow-up was 8.2 years. There were 24,820 death

SUBMITTER: Lee SH 

PROVIDER: S-EPMC8566122 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature