Cardiovascular Outcomes of Obesity According to Menopausal Status: A Nationwide Population-Based Study.

ABSTRACT:

Background

We estimated the effect of obesity on the incidence of cardiovascular disease (CVD) and mortality in women according to menopausal status.

Methods

Women aged 40 to 69 years under routine health check-ups provided by the National Health Insurance Service in 2009 were followed up till 2018 (n=2,208,559).

Results

In premenopausal women, a significant increment of mortality rate was found in underweight and obesity class II (hazard ratio [HR], 1.48; 95% confidence interval [CI], 1.31 to 1.67; and HR, 1.25; 95% CI, 1.12 to 1.39) compared to normal body mass index (BMI); overweight and obesity class I did not affect mortality rate. In postmenopausal women, obesity as well as overweight status reduced the risk of mortality compared to normal BMI (HR, 0.86; 95% CI,

SUBMITTER: Koo BK 

PROVIDER: S-EPMC8566123 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature