Prognostic Value of Triglyceride and Glucose Index for Incident Type 2 Diabetes beyond Metabolic Health and Obesity.

ABSTRACT:

Background

Metabolically healthy obese (MHO) phenotype is metabolically heterogeneous in terms of type 2 diabetes (T2D). Previously, the triglyceride and glucose (TyG) index has been considered for identifying metabolic health and future risk of T2D. This study aimed to evaluate the risk of incident T2D according to obesity status and metabolic health, categorized by four different criteria and the TyG index.

Methods

The study included 39,418 Koreans without T2D at baseline. The risk of T2D was evaluated based on four different definitions of metabolic health and obesity status and according to the baseline TyG index within each metabolic health and obesity group.

Results

During the median follow-up at 38.1 months, 726 individuals developed T2D. Compared with the meta

SUBMITTER: Kim HS 

PROVIDER: S-EPMC8566137 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature