Targeted literature review of current treatments and unmet need in moderate rheumatoid arthritis in the United Kingdom.

ABSTRACT:

Objectives

The burden and treatment landscape of RA is poorly understood. This research aimed to identify evidence on quality of life, caregiver burden, economic burden, treatment patterns and clinical outcomes for patients with moderate RA in the United Kingdom.

Methods

A systematic literature review was performed across multiple databases and screened against pre-defined inclusion criteria.

Results

A total of 2610 records were screened; seven studies presenting evidence for moderate RA were included. These patients were found to incur substantial burden, with moderate to severe levels of disability. Compared with patients in remission, moderate RA patients reported higher levels of disability and decreased EQ-5D utility scores. The majority of patients did not feel

SUBMITTER: Taylor PC 

PROVIDER: S-EPMC8566217 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature