A systematic review and meta-analysis of the incidence rate of Takayasu arteritis.

ABSTRACT:

Objectives

Takayasu arteritis (TAK) is a rare autoimmune rheumatic disease causing large-vessel vasculitis. Onset is typically between the ages of 20 and 30 years. It is associated with substantial morbidity and mortality, notably due to its effects on the cardiovascular system. It has a poorly understood global epidemiology. Our objective was to systematically review the available evidence in order to calculate the incidence rate of TAK.

Methods

Three databases (MEDLINE, PubMed and Embase) were searched in November 2019 and the results were screened by two reviewers. A random effects meta-analysis was then conducted in R to calculate the overall incidence rate. Heterogeneity was assessed using I2. The quality of the studies was assessed using an adapted Newcastle-Ottawa sca

SUBMITTER: Rutter M 

PROVIDER: S-EPMC8566298 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature