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Spousal associations of serum metabolomic profiles by nuclear magnetic resonance spectroscopy.


ABSTRACT: Phenotype-based assortative mating is well established in humans, with the potential for further convergence through a shared environment. To assess the correlation within infertile couples of physical, social, and behavioural characteristics and 155 circulating metabolic measures. Cross sectional study at a tertiary medical center of 326 couples undertaking IVF. Serum lipids, lipoprotein subclasses, and low-molecular weight metabolites as quantified by NMR spectroscopy (155 metabolic measures). Multivariable and quantile regression correlations within couples of metabolite profiles. Couples exhibited statistical correlations of varying strength for most physical, social, and behavioural characteristics including age, height, alcohol consumption, education, smoking status, physical activit

SUBMITTER: Al Rashid K 

PROVIDER: S-EPMC8566506 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature