Prognostic and Predictive Value of Transcription Factors Panel for Digestive System Carcinoma.

ABSTRACT:

Purpose

Digestive system carcinoma is one of the most devastating diseases worldwide. Lack of valid clinicopathological parameters as prognostic factors needs more accurate and effective biomarkers for high-confidence prognosis that guide decision-making for optimal treatment of digestive system carcinoma. The aim of the present study was to establish a novel model to improve prognosis prediction of digestive system carcinoma, with a particular interest in transcription factors (TFs).

Materials and methods

A TF-related prognosis model of digestive system carcinoma with data from TCGA database successively were processed by univariate and multivariate Cox regression analyses. Then, for evaluating the prognostic prediction value of the model, ROC curve and survival analysis we

SUBMITTER: Fang G 

PROVIDER: S-EPMC8566925 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature