SARS-CoV-2 subunit vaccine adjuvants and their signaling pathways.

ABSTRACT:

Introduction

Vaccines are the agreed upon weapon against the COVID-19 pandemic. This review discusses about COVID-19 subunit vaccines adjuvants and their signaling pathways, which could provide a glimpse into the selection of appropriate adjuvants for prospective vaccine development studies.

Areas covered

In the introduction, a brief background about the SARS-CoV-2 pandemic, the vaccine development race and classes of vaccine adjuvants were provided. . The antigen, trial stage, and types of adjuvants were extracted from the included articles and thun assimilated. Finally, the pattern recognition receptors (PRRs), their classes, cognate adjuvants, and potential signaling pathways were comprehended.

Expert opinion

Adjuvants are unsung heroes of subunit vaccines. The in

SUBMITTER: Mekonnen D 

PROVIDER: S-EPMC8567292 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature