Comprehensive profiles and diagnostic value of menopausal-specific gut microbiota in premenopausal breast cancer.

ABSTRACT: In Western countries, breast cancer tends to occur in older postmenopausal women. However, in Asian countries, the proportion of younger premenopausal breast cancer patients is increasing. Increasing evidence suggests that the gut microbiota plays a critical role in breast cancer. However, studies on the gut microbiota in the context of breast cancer have mainly focused on postmenopausal breast cancer. Little is known about the gut microbiota in the context of premenopausal breast cancer. This study aimed to comprehensively explore the gut microbial profiles, diagnostic value, and functional pathways in premenopausal breast cancer patients. Here, we analyzed 267 breast cancer patients with different menopausal statuses and age-matched female controls. The α-diversity was significantly redu

SUBMITTER: Hou MF 

PROVIDER: S-EPMC8569190 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature