Rapid Sequential Implication of the Human Medial Temporal Lobe in Memory Encoding and Recognition.

ABSTRACT: The medial temporal lobe (MTL) is crucial for memory encoding and recognition. The time course of these processes is unknown. The present study juxtaposed encoding and recognition in a single paradigm. Twenty healthy subjects performed a continuous recognition task as brain activity was monitored with a high-density electroencephalography. The task presented New pictures thought to evoke encoding. The stimuli were then repeated up to 4 consecutive times to produce over-familiarity. These repeated stimuli served as "baseline" for comparison with the other stimuli. Stimuli later reappeared after 9-15 intervening items, presumably associated with new encoding and recognition. Encoding-related differences in evoked response potential amplitudes and in spatiotemporal analysis were observed at 1

SUBMITTER: Tautvydaite D 

PROVIDER: S-EPMC8570128 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature