3D Bioprinted Implants for Cartilage Repair in Intervertebral Discs and Knee Menisci.

ABSTRACT: Cartilage defects pose a significant clinical challenge as they can lead to joint pain, swelling and stiffness, which reduces mobility and function thereby significantly affecting the quality of life of patients. More than 250,000 cartilage repair surgeries are performed in the United States every year. The current gold standard is the treatment of focal cartilage defects and bone damage with nonflexible metal or plastic prosthetics. However, these prosthetics are often made from hard and stiff materials that limits mobility and flexibility, and results in leaching of metal particles into the body, degeneration of adjacent soft bone tissues and possible failure of the implant with time. As a result, the patients may require revision surgeries to replace the worn implants or adjacent verteb

SUBMITTER: Perera K 

PROVIDER: S-EPMC8570130 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature