Genetic predispositions moderate the effectiveness of tobacco excise taxes.

ABSTRACT:

Background

Tobacco consumption is one of the leading causes of preventable death. In this study, we analyze whether someone's genetic predisposition to smoking moderates the response to tobacco excise taxes.

Methods

We interact polygenic scores for smoking behavior with state-level tobacco excise taxes in longitudinal data (1992-2016) from the US Health and Retirement Study (N = 12,058).

Results

Someone's genetic propensity to smoking moderates the effect of tobacco excise taxes on smoking behavior along the extensive margin (smoking vs. not smoking) and the intensive margin (the amount of tobacco consumed). In our analysis sample, we do not find a significant gene-environment interaction effect on smoking cessation.

Conclusions

When tobacco excise taxes are re

SUBMITTER: Slob EAW 

PROVIDER: S-EPMC8570524 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature