Vaccine-Associated Disease Enhancement (VADE): Considerations in Postvaccination COVID-19.

ABSTRACT:

Introduction

The COVID-19 pandemic has entered a new phase with the roll-out of several vaccines worldwide at an accelerated phase. The occurrence of a more severe presentation of COVID-19 after vaccination may affect policymakers' decision-making and vaccine uptake by the public. Vaccine-associated disease enhancement (VADE) is the modified presentation of infections in individuals after having received a prior vaccination. Currently, little is known about the potential of vaccine-associated disease enhancement (VADE) following COVID-19 immunization. Case Illustration. We herewith report two patients admitted with confirmed COVID-19 pneumonia with a history of CoronaVac vaccination. The first patient with a relatively milder course of the disease had received two doses of C

SUBMITTER: Tunjungputri RN 

PROVIDER: S-EPMC8570879 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature