Ontology highlight
ABSTRACT:
SUBMITTER: Wang LL
PROVIDER: S-EPMC8571373 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Wang Li-Li LL Luo Jie J He Zhang-Hai ZH Liu Ye-Qing YQ Li Hai-Gang HG Xie Dan D Cai Mu-Yan MY
Cell death & disease 20211105 11
STEAP3 (Six-transmembrane epithelial antigen of the prostate 3, TSAP6, dudulin-2) has been reported to be involved in tumor progression in human malignancies. Nevertheless, how it participates in the progression of human cancers, especially HCC, is still unknown. In the present study, we found that STEAP3 was aberrantly overexpressed in the nuclei of HCC cells. In a large cohort of clinical HCC tissues, high expression level of nuclear STEAP3 was positively associated with tumor differentiation ...[more]