Real-time threshold determination of auditory brainstem responses by cross-correlation analysis.

ABSTRACT: Auditory brainstem response (ABR) serves as an objective indication of auditory perception at a given sound level and is nowadays widely used in hearing function assessment. Despite efforts for automation over decades, ABR threshold determination by machine algorithms remains unreliable and thereby one still relies on visual identification by trained personnel. Here, we described a procedure for automatic threshold determination that can be used in both animal and human ABR tests. The method terminates level averaging of ABR recordings upon detection of time-locked waveform through cross-correlation analysis. The threshold level was then indicated by a dramatic increase in the sweep numbers required to produce "qualified" level averaging. A good match was obtained between the algorithm out

SUBMITTER: Wang H 

PROVIDER: S-EPMC8571499 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature