Assessment of Plasma Phospholipid Very-Long-Chain Saturated Fatty Acid Levels and Healthy Aging.

ABSTRACT:

Importance

Identifying novel factors that protect against age-related diseases and promote healthy aging is critical to public health. Higher levels of circulating very-long-chain saturated fatty acids (VLSFAs) are integrated biomarkers of diet and metabolism shown to have beneficial associations in cardiovascular disease and total mortality, but whether they are associated with overall healthy aging is unknown.

Objective

To examine the association of circulating levels of 3 VLSFAs with unhealthy aging events, including incident chronic disease (cardiovascular disease, cancer, lung disease or severe kidney disease), physical dysfunction, and cognitive decline.

Design, setting, and participants

This cohort study used 1992 to 2014 data from the Cardiovascular Health Stu

SUBMITTER: Bockus LB 

PROVIDER: S-EPMC8571866 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature