Major adverse cardiovascular event definitions used in observational analysis of administrative databases: a systematic review.

ABSTRACT:

Background

Major adverse cardiovascular events (MACE) are increasingly used as composite outcomes in randomized controlled trials (RCTs) and observational studies. However, it is unclear how observational studies most commonly define MACE in the literature when using administrative data.

Methods

We identified peer-reviewed articles published in MEDLINE and EMBASE between January 1, 2010 to October 9, 2020. Studies utilizing administrative data to assess the MACE composite outcome using International Classification of Diseases 9th or 10th Revision diagnosis codes were included. Reviews, abstracts, and studies not providing outcome code definitions were excluded. Data extracted included data source, timeframe, MACE components, code definitions, code positions, and outcome vali

SUBMITTER: Bosco E 

PROVIDER: S-EPMC8571870 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature