Associations between ADIPOQ rs2241766 SNP and breast cancer risk: a systematic review and a meta-analysis.

ABSTRACT:

Purpose

We aimed to conduct a meta-analysis to accurately evaluate the potential association between ADIPOQ rs2241766 gene SNP and breast cancer risk.

Methods

A systematic literature search on Cochrane Library, PubMed, Embase, Web of Science and China National Knowledge Infrastructure (CNKI) identified 8 articles with 1692 cases and 1890 controls. Strength of association was evaluated by pooled odds ratio (OR), 95 % confidence interval (CI) and p value. Funnel plots and Begger's regression test were applied for testing the publication bias. Statistical analysis of all data was performed by Stata 12.0.

Results

The meta-analysis results indicated that the ADIPOQ rs2241766 gene polymorphism did not significantly associated with the risk of breast cancer for these genetic

SUBMITTER: Hu X 

PROVIDER: S-EPMC8572453 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature