Night shift work and cardiovascular disease biomarkers in female nurses.

ABSTRACT:

Background

Night shift work is associated with cardiovascular disease, but its associations with cardiovascular disease biomarkers are unclear. We investigated these associations in a study of female nurses.

Methods

We used data from the Nurses' Health Study II for total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides, C-reactive protein (CRP), and fibrinogen. The sample sizes for our analysis ranged from 458 (fibrinogen) to 3574 (total cholesterol). From questionnaires, we determined the number of night shifts worked in the 2 weeks before blood collection and total years of rotating night shift work. We used quantile regression to estimate differences in biomarker levels by shift work history, adjusting for potenti

SUBMITTER: Johnson CY 

PROVIDER: S-EPMC8572536 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature