Preventing c2c12 muscular cells damage combining magnesium and potassium with vitamin D3 and curcumin.

ABSTRACT:

Background and aim

Physical activity is defined as any bodily movement produced by skeletal muscles which causes energy consumption; moderate and constant physical activity is known to be beneficial and to slow the muscle loss process associated with aging. The aim of the present study was to test, in an in vitro exercise model, the biological effects of a new formulation composed of magnesium and potassium combined with vitamin D and curcumin created to support muscle activity and to prevent hypercontraction damage.

Experimental procedure

C2C12 cells were treated with vitamin D, buffered magnesium bisglycinate, curcumin, and potassium citrate. Cell viability, morpho-functional changes, calcium and magnesium movements, and the main kinases involved in glucose uptake w

SUBMITTER: Molinari C 

PROVIDER: S-EPMC8572722 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature