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A Novel Nutrition-Based Nomogram to Predict Prognosis After Curative Resection of Gastric Cancer.


ABSTRACT: Objective: We sought to investigate the prognostic significance of body composition and weight change during the first 6 months of adjuvant chemotherapy after R0 resection and develop novel nomograms to accurately predict relapse-free survival (RFS) and overall survival (OS). Methods: This retrospective study included 190 patients who underwent curative radical gastrectomy for gastric cancer and received adjuvant chemotherapy. The changes in weight and body composition including skeletal muscle index (SMI), subcutaneous adipose tissue (SAT), and visceral adipose tissue (VAT) were analyzed for 6 months. LASSO Cox regression and multivariate Cox regression were conducted to evaluate other clinical characteristics, which were used to construct a nomogram for the prediction of 3-

SUBMITTER: Zheng H 

PROVIDER: S-EPMC8572887 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature