Humoral response to a third injection of BNT162b2 vaccine in patients on maintenance haemodialysis.

ABSTRACT:

Background

Humoral response against sudden acute respiratory syndrome coronavirus 2 (SARS-CoV-2) after two doses of BNT162b2 (Pfizer-BioNTech) has been proven to be less intense in maintenance dialysis patients as compared with healthy subjects, leading the French authorities to recommend a third injection in this population. Here we investigated the response to the third injection in two cohorts of haemodialysis (HD) patients.

Methods

Data from two prospective observational cohorts were collected. In the first ('systematic') cohort, patients from two HD centres (n = 66) received a third injection of BNT162b2, regardless of the response after two injections. In the second ('conditional') cohort, the injection was only prescribed to patients (n = 34) with no or

SUBMITTER: Dekervel M 

PROVIDER: S-EPMC8573007 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature