Gastrointestinal stromal tumors: associations between contrast-enhanced CT images and KIT exon 11 gene mutation.

ABSTRACT:

Background

Mutation screening for gastrointestinal stromal tumor (GIST) is crucial and the c kit gene (KIT) exon 11 mutation is the most common type. This study aimed to explore the associations between GIST with KIT exon 11 mutation and contrast-enhanced computed tomography (CT) images.

Methods

Pathologically proven GISTs with definitive genotype testing results in our hospital were retrospectively included. Abdominal contrast-enhanced CT images were analyzed. Conventional CT image features and radiomic features were recorded and extracted to build the following models: model _[CT], model _{[radiomic + clinic]} and model _{[CT + radiomic + clinic]}. The diagnostic performances of GISTs with KIT exon 11 mutation and KIT exon 11 deletion involving co

SUBMITTER: Liu X 

PROVIDER: S-EPMC8573436 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature