Narrative review of gene modification: applications in three-dimensional (3D) bioprinting.

ABSTRACT:

Objective

This article focused on the application scenarios of three-dimensional (3D) bioprinting and gene-editing technology in various medical fields, including gene therapy, tissue engineering, tumor microenvironment simulation, tumor model construction, cancer regulation and expression, osteogenesis, and skin and vascular regeneration, and summarizing its development prospects and shortcomings.

Background

3D bioprinting is a process based on additive manufacturing that uses biological materials as the microenvironment living cells. The scaffolds and carriers manufactured by 3D bioprinting technology provide a safe, efficient, and economical platform for genes, cells, and biomolecules. Gene modification refers to replacing, splicing, silencing, editing, controlling or ina

SUBMITTER: Fu B 

PROVIDER: S-EPMC8573440 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature