Morphological Reconstruction Improves Microvessel Mapping in Super-Resolution Ultrasound.

ABSTRACT: Generation of super-resolution (SR) ultrasound (US) images, created from the successive localization of individual microbubbles in the circulation, has enabled the visualization of microvascular structure and flow at a level of detail that was not possible previously. Despite rapid progress, tradeoffs between spatial and temporal resolution may challenge the translation of this promising technology to the clinic. To temper these tradeoffs, we propose a method based on morphological image reconstruction. This method can extract from ultrafast contrast-enhanced US (CEUS) images hundreds of microbubble peaks per image (312-by-180 pixels) with intensity values varying by an order of magnitude. Specifically, it offers a fourfold increase in the number of peaks detected per frame, requires on th

SUBMITTER: Schoen S 

PROVIDER: S-EPMC8574223 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature