Associations between fatty acid composition in serum cholesteryl esters and liver fat, basal fat oxidation, and resting energy expenditure: a population-based study.

ABSTRACT:

Background

We have repeatedly shown in short-term feeding trials that a high intake of dietary n-6 PUFAs, i.e. linoleic acid, prevents liver fat accumulation compared with saturated fat. However, population-based data is lacking and the mechanisms behind such effects are unclear.

Objective

To investigate associations between serum cholesteryl ester (CE) fatty acids and liver fat, basal fat oxidation [respiratory quotient (RQ)], and resting energy expenditure (REE). We hypothesized that PUFA in particular is inversely associated with liver fat and that such a relation is partly explained by a PUFA-induced increase in basal fat oxidation or REE.

Methods

Cross-sectional analyses using linear regression models in a population-based cohort with data on serum CE fatty acid

SUBMITTER: Friden M 

PROVIDER: S-EPMC8574708 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature