A Systematic Review on the Therapeutic Relevance of Hydroxychloroquine/Chloroquine in the Management of COVID-19.

ABSTRACT:

Background

The coronavirus disease-2019 (COVID-19) pandemic is coming to the fore and has surfaced as a public health emergency of international concern. The lack of vaccines or an effective treatment has led to the global hunt for potential pharmaceuticals in adequately managing this disease. This systematic review highlights the efficacy of chloroquine and its derivative hydroxychloroquine in the treatment of COVID-19 and also explores the safety profile of these drugs.

Methods

EMBASE, COCHRANE, and PubMed databases were searched for studies on the use of hydroxychloroquine or chloroquine in the treatment of COVID-19.

Results

Twenty articles were selected including expert opinions, National Guidelines, three small randomized controlled trials, and one prospective st

SUBMITTER: Mccabe G 

PROVIDER: S-EPMC8575213 | biostudies-literature | 2021 Jul-Sep

REPOSITORIES: biostudies-literature