Inpatient compliance with venous thromboembolism prophylaxis after orthopaedic trauma: results from a randomized controlled trial of aspirin versus low molecular weight heparin.

ABSTRACT:

Objectives

To compare inpatient compliance with venous thromboembolism prophylaxis regimens.

Design

A secondary analysis of patients enrolled in the ADAPT (A Different Approach to Preventing Thrombosis) randomized controlled trial.

Setting

Level I trauma center.

Patients/participants

Patients with operative extremity or any pelvic or acetabular fracture requiring venous thromboembolism prophylaxis.

Intervention

We compared patients randomized to receive either low molecular weight heparin (LMWH) 30 mg or aspirin 81 mg BID during their inpatient admission.

Main outcome measurements

The primary outcome measure was the number of doses missed compared with prescribed number of doses.

Results

A total of 329 patients were randomized to receive ei

SUBMITTER: Haac BE 

PROVIDER: S-EPMC8575420 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature