Emerging roles of left ventricular assist device therapy as bridge to transplant in an Asian city with scarce heart transplant donor.

ABSTRACT:

Background

Left ventricular assist device (LVAD) has been increasingly used in patients with advanced heart failure. This study aimed to assess the impact of implementation of LVAD therapy on heart transplantation (HTx) service in Hong Kong (HK).

Methods

LVAD program was started in 2010 in HK and patients who had been put on HTx waiting list since the start of HTx program in HK from 1992 to 2020 were included for analysis. Survival on HTx waiting list between pre-LVAD era 1992-2009 and post-LVAD era 2010-2020 were analyzed by Kaplan-Meier method and compared by log-rank test. Multivariate analysis by time-dependent Cox-proportional hazard model was used to identify independent predictors of HTx waiting list mortality.

Results

A total of 478 heart transplant listing ep

SUBMITTER: Wong KL 

PROVIDER: S-EPMC8575832 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature