Correlation of EGFR G873R mutation with prognosis of docetaxel in non-small cell lung cancer.

ABSTRACT:

Background

Clinical features of epidermal growth factor receptor (EGFR) mutations have been commonly recognized in variant cancers. The role of EGFR mutations in non-small cell lung cancer (NSCLC) has spurred research and drug development efforts. However, there are still mutations that have not been widely reported, and their influences on NSCLC have not been fully elucidated; EGFR G873R mutation is just one of them. The aim of this study was to investigate the correlation between EGFR G873R mutation and the prognosis of chemotherapy in NSCLC.

Methods

A total of 54 patients with NSCLC were enrolled in this study. Immunohistochemical staining was used to detect the expression of EGFR. A DNA extraction kit (GeneRead DNA FFPE Kit) was used to

SUBMITTER: Tian Y 

PROVIDER: S-EPMC8575840 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature