Remote Ischemic Conditioning in Ischemic Stroke and Myocardial Infarction: Similarities and Differences.

ABSTRACT: Acute myocardial infarction and ischemic stroke are leading causes of morbidity and mortality worldwide. Although reperfusion therapies have greatly improved the outcomes of patients with these conditions, many patients die or are severely disabled despite complete reperfusion. It is therefore important to identify interventions that can prevent progression to ischemic necrosis and limit ischemia-reperfusion injury. A possible strategy is ischemic conditioning, which consists of inducing ischemia - either in the ischemic organ or in another body site [i.e., remote ischemic conditioning (RIC), e.g., by inflating a cuff around the patient's arm or leg]. The effects of ischemic conditioning have been studied, alone or in combination with revascularization techniques. Based on the timing (befo

SUBMITTER: Saccaro LF 

PROVIDER: S-EPMC8576053 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature