Global coagulation assays in patients with diabetes mellitus.

ABSTRACT:

Background

There is significant heterogeneity in the incidence and severity of diabetes-associated vascular complications and there is no routine biomarker that accurately predicts these outcomes. This pilot study investigates the role of global coagulation assays in patients with diabetes mellitus.

Methods

In this cross-sectional study, patients with diabetes not on anticoagulation or dialysis and without active malignancy were recruited from endocrinology clinics. Blood samples were collected for global coagulation assays including thromboelastography (TEG), thrombin generation using calibrated automated thrombogram (CAT), and fibrin generation and fibrinolysis using the overall hemostatic potential (OHP) assay. The results were compared with healthy controls.

Results</

SUBMITTER: Lim HY 

PROVIDER: S-EPMC8576266 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature