Ontology highlight
ABSTRACT:
SUBMITTER: D S P
PROVIDER: S-EPMC8576531 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
D S Prabakaran P Chaturvedi Pankaj Kumar PK Shimokawa Takashi T Kim Ki-Hwan KH Park Woo-Yoon WY
Frontiers in oncology 20211026
The effects of Carbon ion radiation (C-ion) alone or in combination with fused toes homolog (FTS) silencing on Notch signaling were investigated in uterine cervical cancer cell lines (ME180 and CaSki). In both cell lines, upon irradiation with C-ion, the expression of Notch signaling molecules (Notch1, 2, 3 and cleaved Notch1), γ-secretase complex molecules and FTS was upregulated dose-dependently (1, 2 and 4 Gy) except Notch1 in ME180 cells where the change in expression was not significant. Ho ...[more]