Preoperative prediction of gastrointestinal stromal tumors with high Ki-67 proliferation index based on CT features.

ABSTRACT:

Background

To determine whether preoperative computed tomography (CT) features can be used for the prediction of gastrointestinal stromal tumors (GISTs) with a high Ki-67 proliferation index (Ki-67 PI).

Methods

A total of 198 patients with surgically and pathologically proven GISTs were retrospectively included. All GISTs were divided into a low Ki-67 PI group (<10%) and a high Ki-67 PI group (≥10%). All imaging features were blindly interpreted by two radiologists. Receiver operating characteristic (ROC) curve analyses were conducted to evaluate the predictive performance of the imaging features.

Results

Imaging features were found to be significantly different between the low and the high Ki-67 PI groups (P<0.05). Wall thickness of necrosis showed the highest predic

SUBMITTER: Yang CW 

PROVIDER: S-EPMC8576677 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature