Awake prone positioning and oxygen therapy in patients with COVID-19: the APRONOX study.

ABSTRACT:

Background

The awake prone positioning strategy for patients with acute respiratory distress syndrome is a safe, simple and cost-effective technique used to improve hypoxaemia. We aimed to evaluate intubation and mortality risk in patients with coronavirus disease 2019 (COVID-19) who underwent awake prone positioning during hospitalisation.

Methods

In this retrospective, multicentre observational study conducted between 1 May 2020 and 12 June 2020 in 27 hospitals in Mexico and Ecuador, nonintubated patients with COVID-19 managed with awake prone or awake supine positioning were included to evaluate intubation and mortality risk through logistic regression models; multivariable and centre adjustment, propensity score analyses, and E-values were calculated to limit confounding

SUBMITTER: Perez-Nieto OR 

PROVIDER: S-EPMC8576803 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature