Age moderates the relationship between affective response inhibition and bipolar disorder in adults.

ABSTRACT:

Background

Patients with bipolar disorder (BD) often have impairments in neurocognition, including affective processing and affective response inhibition. While studies suggest that cognitive control in general may decline with age in BD, less is known about age-related changes in response inhibition to emotionally salient information.

Methods

258 participants with BD and 54 healthy controls, ages 18-70, completed the Cambridge Neuropsychological Test Automated Battery (CANTAB) Affective Go/No-Go task to assess affective response inhibition to positive and negative valenced stimuli. We examined the relationship between BD and affective response inhibition (number of commission and omission errors and reaction time), as well as a potential moderating effect of age, using mixe

SUBMITTER: Slate SR 

PROVIDER: S-EPMC8577218 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature