Genetic Polymorphisms in Pharmaceuticals and Chemotherapy.

ABSTRACT: The study of genetic polymorphisms has significantly advanced the field of personalized medicine. Polymorphism of genes influence the efficacy of drugs used for treating medical conditions such as depression, cardiac diseases, thromboembolic disorders, oncological diseases, etc. The study of genetic polymorphism is beneficial for drug safety as well as for assessing therapeutic outcomes. Understanding and detecting genetic polymorphisms early on in patients can be useful in selecting the correct chemotherapeutic agent and appropriate dosage for a patient. Knowing the genetic profile of a patient and the interindividual response to various drugs significantly influences the proper selection of medication - a key step towards personalized medicine. Polymorphisms also make patients susceptibl

SUBMITTER: Gummadi AC 

PROVIDER: S-EPMC8577603 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature